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Sympathetic Neurotransmitters Modulate Osteoclastogenesis and Osteoclast Activity in the Context of Collagen-Induced Arthritis

Excessive synovial osteoclastogenesis is a hallmark of rheumatoid arthritis (RA). Concomitantly, local synovial changes comprise neuronal components of the peripheral sympathetic nervous system. Here, we wanted to analyze if collagen-induced arthritis (CIA) alters bone marrow-derived macrophage (BMM...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Muschter, Dominique, Schäfer, Nicole, Stangl, Hubert, Straub, Rainer H., Grässel, Susanne
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4592252/
https://ncbi.nlm.nih.gov/pubmed/26431344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0139726
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