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Steroid Receptor Coactivator-3 (SRC-3/AIB1) as a Novel Therapeutic Target in Triple Negative Breast Cancer and Its Inhibition with a Phospho-Bufalin Prodrug

Triple negative breast cancer (TNBC) has the poorest prognosis of all types of breast cancer and currently lacks efficient targeted therapy. Chemotherapy is the traditional standard-of-care for TNBC, but is frequently accompanied by severe side effects. Despite the fact that high expression of stero...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Song, Xianzhou, Zhang, Chengwei, Zhao, Mingkun, Chen, Hui, Liu, Xing, Chen, Jianwei, Lonard, David M., Qin, Li, Xu, Jianming, Wang, Xiaosong, Li, Feng, O’Malley, Bert W., Wang, Jin
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4592245/
https://ncbi.nlm.nih.gov/pubmed/26431029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0140011
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