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The Cellular Localization of Human Cytomegalovirus Glycoprotein Expression Greatly Influences the Frequency and Functional Phenotype of Specific CD4(+) T Cell Responses

CMV infection is a significant cause of morbidity and mortality in immunocompromised individuals, and the development of a vaccine is of high priority. Glycoprotein B (gB) is a leading vaccine candidate but the glycoprotein H (gH) pentameric complex is now recognized as the major target for neutrali...

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Опубликовано в: :J Immunol
Главные авторы: Pachnio, Annette, Zuo, Jianmin, Ryan, Gordon B., Begum, Jusnara, Moss, Paul A. H.
Формат: Artigo
Язык:Inglês
Опубликовано: AAI 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4592104/
https://ncbi.nlm.nih.gov/pubmed/26363059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500696
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