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GWAS with longitudinal phenotypes: performance of approximate procedures

Analysis of genome-wide association studies with longitudinal data using standard procedures, such as linear mixed model (LMM) fitting, leads to discouragingly long computation times. There is a need to speed up the computations significantly. In our previous work (Sikorska et al: Fast linear mixed...

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Detalhes bibliográficos
Publicado no:Eur J Hum Genet
Main Authors: Sikorska, Karolina, Montazeri, Nahid Mostafavi, Uitterlinden, André, Rivadeneira, Fernando, Eilers, Paul HC, Lesaffre, Emmanuel
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4592098/
https://ncbi.nlm.nih.gov/pubmed/25712081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2015.1
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