Extensive genome-wide autozygosity in the population isolates of Daghestan

Isolated populations are valuable resources for mapping disease genes, as inbreeding increases genome-wide homozygosity and enhances the ability to map disease alleles on a genetically uniform background within a relatively homogenous environment. The populations of Daghestan are thought to have res...

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Publicat a:Eur J Hum Genet
Autors principals: Karafet, Tatiana M, Bulayeva, Kazima B, Bulayev, Oleg A, Gurgenova, Farida, Omarova, Jamilia, Yepiskoposyan, Levon, Savina, Olga V, Veeramah, Krishna R, Hammer, Michael F
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4592092/
https://ncbi.nlm.nih.gov/pubmed/25604856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2014.299
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