Liposomal n-butylidenephthalide protects the drug from oxidation and enhances its antitumor effects in glioblastoma multiforme

BACKGROUND: The natural compound n-butylidenephthalide (BP) can pass through the blood–brain barrier to inhibit the growth of glioblastoma multiforme tumors. However, BP has an unstable structure that reduces its antitumor activity and half-life in vivo. OBJECTIVE: The aim of this study is to design...

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Bibliografiske detaljer
Udgivet i:Int J Nanomedicine
Main Authors: Lin, Yu-Ling, Chang, Kai-Fu, Huang, Xiao-Fan, Hung, Che-Lun, Chen, Shyh-Chang, Chao, Wan-Ru, Liao, Kuang-Wen, Tsai, Nu-Man
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2015
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4592058/
https://ncbi.nlm.nih.gov/pubmed/26451107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S85790
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