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A New Method for Detecting Associations with Rare Copy-Number Variants

Copy number variants (CNVs) play an important role in the etiology of many diseases such as cancers and psychiatric disorders. Due to a modest marginal effect size or the rarity of the CNVs, collapsing rare CNVs together and collectively evaluating their effect serves as a key approach to evaluating...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS Genet
Hauptverfasser: Tzeng, Jung-Ying, Magnusson, Patrik K. E., Sullivan, Patrick F., Szatkiewicz, Jin P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4592002/
https://ncbi.nlm.nih.gov/pubmed/26431523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005403
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