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Fibrogenesis in Primary Myelofibrosis: Diagnostic, Clinical, and Therapeutic Implications
Primary myelofibrosis is a stem cell-derived clonal malignancy characterized by unchecked proliferation of myeloid cells, resulting in bone marrow fibrosis, osteosclerosis, and pathologic angiogenesis. Bone marrow fibrosis (BMF) plays a central role in the pathophysiology of the disease. This review...
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出版年: | Oncologist |
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主要な著者: | , , , |
フォーマット: | Artigo |
言語: | Inglês |
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AlphaMed Press
2015
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4591957/ https://ncbi.nlm.nih.gov/pubmed/26304912 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2015-0094 |
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