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Potential role of hypoxia in early stages of Hodgkin lymphoma pathogenesis

A unique feature of the germinal center B cell-derived Hodgkin and Reed/Sternberg cells of classical Hodgkin lymphoma is their lost B cell phenotype and the aberrant expression of factors of other hematopoietic cell types, including ID2 and NOTCH1. As cellular dedifferentiation and upregulation of I...

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Bibliografiske detaljer
Udgivet i:Haematologica
Main Authors: Wein, Frederik, Otto, Teresa, Lambertz, Pascal, Fandrey, Joachim, Hansmann, Martin-Leo, Küppers, Ralf
Format: Artigo
Sprog:Inglês
Udgivet: Ferrata Storti Foundation 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4591764/
https://ncbi.nlm.nih.gov/pubmed/26160878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2015.127498
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