Obesity-associated hypertension is ameliorated in patients with TLR4 single nucleotide polymorphism (SNP) rs4986790

BACKGROUND: Obesity is strongly associated with hypertension. Despite numerous mechanistic links the association is not fully understood. Western diet increases uptake of Toll-Like receptor 4 (TLR4) ligands such as free fatty acids or endotoxin. We recently demonstrated that TLR4 ligands are involve...

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Vydáno v:J Inflamm (Lond)
Hlavní autoři: Schneider, Simon, Hoppmann, Petra, Koch, Werner, Kemmner, Stephan, Schmaderer, Christoph, Renders, Lutz, Kastrati, Adnan, Laugwitz, Karl-Ludwig, Heemann, Uwe, Baumann, Marcus
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4591702/
https://ncbi.nlm.nih.gov/pubmed/26435700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12950-015-0100-5
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