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Challenges and Opportunities for T-Cell-Mediated Strategies to Eliminate HIV Reservoirs

HIV’s ability to establish latent reservoirs of reactivation-competent virus is the major barrier to cure. “Shock and kill” methods consisting of latency-reversing agents (LRAs) followed by elimination of reactivating cells through cytopathic effects are under active development. However, the clinic...

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Vydáno v:Front Immunol
Hlavní autoři: Brockman, Mark A., Jones, R. Brad, Brumme, Zabrina L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4591506/
https://ncbi.nlm.nih.gov/pubmed/26483795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2015.00506
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