Pigment epithelium-derived factor as a multifunctional regulator of wound healing

During dermal wound repair, hypoxia-driven proliferation results in dense but highly permeable, disorganized microvascular networks, similar to those in solid tumors. Concurrently, activated dermal fibroblasts generate an angiopermissive, provisional extracellular matrix (ECM). Unlike cancers, wound...

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Pubblicato in:Am J Physiol Heart Circ Physiol
Autori principali: Wietecha, Mateusz S., Król, Mateusz J., Michalczyk, Elizabeth R., Chen, Lin, Gettins, Peter G., DiPietro, Luisa A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2015
Soggetti:
Vascular Biology and Microcirculation
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4591402/
https://ncbi.nlm.nih.gov/pubmed/26163443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00153.2015
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