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Fructose-induced increases in expression of intestinal fructolytic and gluconeogenic genes are regulated by GLUT5 and KHK

Marked increases in fructose consumption have been tightly linked to metabolic diseases. One-third of ingested fructose is metabolized in the small intestine, but the underlying mechanisms regulating expression of fructose-metabolizing enzymes are not known. We used genetic mouse models to test the...

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Bibliografske podrobnosti
izdano v:Am J Physiol Regul Integr Comp Physiol
Main Authors: Patel, Chirag, Douard, Veronique, Yu, Shiyan, Tharabenjasin, Phuntila, Gao, Nan, Ferraris, Ronaldo P.
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4591376/
https://ncbi.nlm.nih.gov/pubmed/26084694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00128.2015
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