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Micro-RNA Binding Site Polymorphisms in the WFS1 Gene Are Risk Factors of Diabetes Mellitus

The absolute or relative lack of insulin is the key factor in the pathogenesis of diabetes mellitus. Although the connection between loss of function mutations of the WFS1 gene and DIDMOAD-syndrome including diabetes mellitus underpins the significance of wolframin in the pathogenesis, exact role of...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Elek, Zsuzsanna, Németh, Nóra, Nagy, Géza, Németh, Helga, Somogyi, Anikó, Hosszufalusi, Nóra, Sasvári-Székely, Mária, Rónai, Zsolt
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4591293/
https://ncbi.nlm.nih.gov/pubmed/26426397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0139519
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