Dissecting Fission Yeast Shelterin Interactions via MICro-MS Links Disruption of Shelterin Bridge to Tumorigenesis

Shelterin, a six-member complex, protects telomeres from nucleolytic attack and regulates their elongation by telomerase. Here, we have developed a strategy, called MICro-MS (Mapping Interfaces via Crosslinking-Mass Spectrometry), that combines crosslinking-mass spectrometry and phylogenetic analysi...

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Publicat a:Cell Rep
Autors principals: Liu, Jinqiang, Yu, Clinton, Hu, Xichan, Kim, Jin-Kwang, Bierma, Jan C., Jun, Hyun-Ik, Rychnovsky, Scott D., Huang, Lan, Qiao, Feng
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4591219/
https://ncbi.nlm.nih.gov/pubmed/26365187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.08.043
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