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Nuclear localization of mouse Ku70 in interphase cells and focus formation of mouse Ku70 at DNA damage sites immediately after irradiation

To elucidate the mechanisms of DNA repair pathway is critical for developing next-generation radiotherapies and chemotherapeutic drugs for cancer. Ionizing radiation and many chemotherapeutic drugs kill tumor cells mainly by inducing DNA double-strand breaks (DSBs). The classical nonhomologous DNA-e...

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Bibliografske podrobnosti
izdano v:J Vet Med Sci
Main Authors: KOIKE, Manabu, YUTOKU, Yasutomo, KOIKE, Aki
Format: Artigo
Jezik:Inglês
Izdano: The Japanese Society of Veterinary Science 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4591156/
https://ncbi.nlm.nih.gov/pubmed/25947323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1292/jvms.14-0651
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