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Nuclear localization of mouse Ku70 in interphase cells and focus formation of mouse Ku70 at DNA damage sites immediately after irradiation

To elucidate the mechanisms of DNA repair pathway is critical for developing next-generation radiotherapies and chemotherapeutic drugs for cancer. Ionizing radiation and many chemotherapeutic drugs kill tumor cells mainly by inducing DNA double-strand breaks (DSBs). The classical nonhomologous DNA-e...

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Detalhes bibliográficos
Publicado no:J Vet Med Sci
Main Authors: KOIKE, Manabu, YUTOKU, Yasutomo, KOIKE, Aki
Formato: Artigo
Idioma:Inglês
Publicado em: The Japanese Society of Veterinary Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4591156/
https://ncbi.nlm.nih.gov/pubmed/25947323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1292/jvms.14-0651
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