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Functional Impact and Evolution of a Novel Human Polymorphic Inversion That Disrupts a Gene and Creates a Fusion Transcript

Despite many years of study into inversions, very little is known about their functional consequences, especially in humans. A common hypothesis is that the selective value of inversions stems in part from their effects on nearby genes, although evidence of this in natural populations is almost none...

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Dettagli Bibliografici
Pubblicato in:PLoS Genet
Autori principali: Puig, Marta, Castellano, David, Pantano, Lorena, Giner-Delgado, Carla, Izquierdo, David, Gayà-Vidal, Magdalena, Lucas-Lledó, José Ignacio, Esko, Tõnu, Terao, Chikashi, Matsuda, Fumihiko, Cáceres, Mario
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4591017/
https://ncbi.nlm.nih.gov/pubmed/26427027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005495
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