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New genes drive the evolution of gene interaction networks in the human and mouse genomes

BACKGROUND: The origin of new genes with novel functions creates genetic and phenotypic diversity in organisms. To acquire functional roles, new genes must integrate into ancestral gene-gene interaction (GGI) networks. The mechanisms by which new genes are integrated into ancestral networks, and the...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Zhang, Wenyu, Landback, Patrick, Gschwend, Andrea R., Shen, Bairong, Long, Manyuan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4590697/
https://ncbi.nlm.nih.gov/pubmed/26424194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-015-0772-4
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