Intrathecal morphine attenuates acute opioid tolerance secondary to remifentanil infusions during spinal surgery in adolescents

INTRODUCTION: The unique pharmacokinetic properties of remifentanil with a context-sensitive half-life unaffected by length of infusion contribute to its frequent use during anesthetic management during posterior spinal fusion in children and adolescents. However, its intraoperative administration c...

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Bibliographic Details
Published in:J Pain Res
Main Authors: Tripi, Paul A, Kuestner, Matthew E, Poe-Kochert, Connie S, Rubin, Kasia, Son-Hing, Jochen P, Thompson, George H, Tobias, Joseph D
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2015
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4590583/
https://ncbi.nlm.nih.gov/pubmed/26445559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JPR.S88687
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