Lansoprazole Is Associated with Worsening Asthma Control in Children with the CYP2C19 Poor Metabolizer Phenotype

Rationale: Gastric acid blockade in children with asymptomatic acid reflux has not improved asthma control in published studies. There is substantial population variability regarding metabolism of and response to proton pump inhibitors based on metabolizer phenotype. How metabolizer phenotype affect...

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Bibliografische gegevens
Gepubliceerd in:Ann Am Thorac Soc
Hoofdauteurs: Lang, Jason E., Holbrook, Janet T., Mougey, Edward B., Wei, Christine Y., Wise, Robert A., Teague, W. Gerald, Lima, John J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Thoracic Society 2015
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Original Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4590024/
https://ncbi.nlm.nih.gov/pubmed/25844821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1513/AnnalsATS.201408-391OC
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