Lansoprazole Is Associated with Worsening Asthma Control in Children with the CYP2C19 Poor Metabolizer Phenotype

Rationale: Gastric acid blockade in children with asymptomatic acid reflux has not improved asthma control in published studies. There is substantial population variability regarding metabolism of and response to proton pump inhibitors based on metabolizer phenotype. How metabolizer phenotype affect...

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Bibliografske podrobnosti
izdano v:Ann Am Thorac Soc
Main Authors: Lang, Jason E., Holbrook, Janet T., Mougey, Edward B., Wei, Christine Y., Wise, Robert A., Teague, W. Gerald, Lima, John J.
Format: Artigo
Jezik:Inglês
Izdano: American Thoracic Society 2015
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4590024/
https://ncbi.nlm.nih.gov/pubmed/25844821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1513/AnnalsATS.201408-391OC
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