A phase I dose-escalation clinical trial of a peptide-based human papillomavirus therapeutic vaccine with Candida skin test reagent as a novel vaccine adjuvant for treating women with biopsy-proven cervical intraepithelial neoplasia 2/3

PURPOSE: Non-surgical treatments for cervical intraepithelial neoplasia 2/3 (CIN2/3) are needed as surgical treatments have been shown to double preterm delivery rate. The goal of this study was to demonstrate safety of a human papillomavirus (HPV) therapeutic vaccine called PepCan, which consists o...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Greenfield, William W, Stratton, Shawna L, Myrick, Rebecca S, Vaughn, Rita, Donnalley, Lisa M, Coleman, Hannah N, Mercado, Maria, Moerman-Herzog, Andrea M, Spencer, Horace J, Andrews-Collins, Nancy R, Hitt, Wilbur C, Low, Gordon M, Manning, Nirvana A, McKelvey, Samantha S, Smith, Dora, Smith, Michael V, Phillips, Amy M, Quick, C Matthew, Jeffus, Susanne K, Hutchins, Laura F, Nakagawa, Mayumi
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4590015/
https://ncbi.nlm.nih.gov/pubmed/26451301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1031439
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