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Using three-color chromosome painting to test chromosome aberration models.

Ionizing radiation induces DNA double-strand breaks (DSB), which interact pairwise to produce chromosome aberrations. There have long been two main competing theories of such pairwise DSB-DSB interactions. The "classical" theory asserts that an unrepaired DSB makes two ends that separate within the...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Lucas, J N, Sachs, R K
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1993
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45898/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8434009/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.4.1484
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