MeSiC: A Model-Based Method for Estimating 5 mC Levels at Single-CpG Resolution from MeDIP-seq

As the fifth base in mammalian genome, 5-methylcytosine (5 mC) is essential for many biological processes including normal development and disease. Methylated DNA immunoprecipitation sequencing (MeDIP-seq), which uses anti-5 mC antibodies to enrich for methylated fraction of the genome, is widely us...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Xiao, Yun, Yu, Fulong, Pang, Lin, Zhao, Hongying, Liu, Ling, Zhang, Guanxiong, Liu, Tingting, Zhang, Hongyi, Fan, Huihui, Zhang, Yan, Pang, Bo, Li, Xia
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4589794/
https://ncbi.nlm.nih.gov/pubmed/26424089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14699
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