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NSAIDs Ibuprofen, Indometacin, and Diclofenac do not interact with Farnesoid X Receptor
The nuclear farnesoid X receptor (FXR) is a ligand activated transcription factor and acts as cellular sensor for bile acids. In this role, FXR is a highly important liver protector and FXR inhibition by antagonists or knockout has shown several deleterious effects. A recent report characterized non...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4589779/ https://ncbi.nlm.nih.gov/pubmed/26424593 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14782 |
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