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Beyond CD19: Opportunities for Future Development of Targeted Immunotherapy in Pediatric Relapsed-Refractory Acute Leukemia

Chimeric antigen receptor (CAR) T cell therapy has been used as a targeted approach in cancer therapy. Relapsed and refractory acute leukemia in pediatrics has been difficult to treat with conventional therapy due to dose-limiting toxicities. With the recent success of CD 19 CAR in pediatric patient...

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Detalhes bibliográficos
Publicado no:Front Pediatr
Main Authors: Shalabi, Haneen, Angiolillo, Anne, Fry, Terry J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4589648/
https://ncbi.nlm.nih.gov/pubmed/26484338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fped.2015.00080
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