Central GLP-1 receptor signalling accelerates plasma clearance of triacylglycerol and glucose by activating brown adipose tissue in mice

AIMS/HYPOTHESIS: Glucagon-like peptide 1 (GLP-1) receptor (GLP-1R) agonism, used in the treatment of type 2 diabetes, has recently been shown to increase thermogenesis via the brain. As brown adipose tissue (BAT) produces heat by burning triacylglycerol (TG) and takes up glucose for de novo lipogene...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Diabetologia
Hlavní autoři: Kooijman, Sander, Wang, Yanan, Parlevliet, Edwin T., Boon, Mariëtte R., Edelschaap, David, Snaterse, Gido, Pijl, Hanno, Romijn, Johannes A., Rensen, Patrick C. N.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Berlin Heidelberg 2015
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4589565/
https://ncbi.nlm.nih.gov/pubmed/26254578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-015-3727-0
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky