Elevated HbA(1c) levels and the accumulation of differentiated T cells in CMV(+) individuals

AIMS/HYPOTHESIS: Biological ageing of the immune system, or immunosenescence, predicts poor health and increased mortality. A hallmark of immunosenescence is the accumulation of differentiated cytotoxic T cells (CD27(−)CD45RA(+/−); or dCTLs), partially driven by infection with the cytomegalovirus (C...

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Detalhes bibliográficos
Publicado no:Diabetologia
Main Authors: Rector, Jerrald L., Thomas, G. Neil, Burns, Victoria E., Dowd, Jennifer B., Herr, Raphael M., Moss, Paul A., Jarczok, Marc N., Hoffman, Kristina, Fischer, Joachim E., Bosch, Jos A.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4589544/
https://ncbi.nlm.nih.gov/pubmed/26290049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-015-3731-4
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