DJ-1 Protects Pancreatic Beta Cells from Cytokine- and Streptozotocin-Mediated Cell Death

A hallmark feature of type 1 and type 2 diabetes mellitus is the progressive dysfunction and loss of insulin-producing pancreatic beta cells, and inflammatory cytokines are known to trigger beta cell death. Here we asked whether the anti-oxidant protein DJ-1 encoded by the Parkinson’s disease gene P...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Jain, Deepak, Weber, Gesine, Eberhard, Daniel, Mehana, Amir E., Eglinger, Jan, Welters, Alena, Bartosinska, Barbara, Jeruschke, Kay, Weiss, Jürgen, Päth, Günter, Ariga, Hiroyoshi, Seufert, Jochen, Lammert, Eckhard
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4589499/
https://ncbi.nlm.nih.gov/pubmed/26422139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138535
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