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High-Throughput, Data-Rich Cellular RNA Device Engineering

Methods for rapidly assessing sequence-structure-function landscapes and developing conditional gene-regulatory devices are critical to our ability to manipulate and interface with biology. We describe a framework for engineering RNA devices from preexisting aptamers that exhibit ligand-responsive r...

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Bibliografische gegevens
Gepubliceerd in:Nat Methods
Hoofdauteurs: Townshend, Brent, Kennedy, Andrew B., Xiang, Joy S., Smolke, Christina D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4589471/
https://ncbi.nlm.nih.gov/pubmed/26258292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.3486
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