Antithrombin III/SerpinC1 insufficiency exacerbates renal ischemia/reperfusion injury

Antithrombin III, encoded by SerpinC1, is a major anti-coagulation molecule in vivo and has anti-inflammatory effects. We found that patients with low antithrombin III activities presented a higher risk of developing acute kidney injury after cardiac surgery. To study this further, we generated Serp...

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Vydáno v:Kidney Int
Hlavní autoři: Wang, Feng, Zhang, Guangyuan, Lu, Zeyuan, Geurts, Aron M, Usa, Kristie, Jacob, Howard J, Cowley, Allen W, Wang, Niansong, Liang, Mingyu
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2015
Témata:
Basic Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4589441/
https://ncbi.nlm.nih.gov/pubmed/26108065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2015.176
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