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Expression of the Stem Cell Factor Nestin in Malignant Pleural Mesothelioma Is Associated with Poor Prognosis

BACKGROUND: The epithelioid and sarcomatoid histologic variants of malignant pleural mesothelioma (MPM) can be considered as E- and M-parts of the epithelial-mesenchymal transition (EMT) axis; the biphasic being an intermediate. EMT is associated with an increase of stem cell (SC) traits. We correla...

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Veröffentlicht in:PLoS One
Hauptverfasser: Thies, Svenja, Friess, Martina, Frischknecht, Lukas, Korol, Dimitri, Felley-Bosco, Emanuela, Stahel, Rolf, Vrugt, Bart, Weder, Walter, Opitz, Isabelle, Soltermann, Alex
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4589394/
https://ncbi.nlm.nih.gov/pubmed/26421614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0139312
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