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Molecular Binding Mechanism of TtgR Repressor to Antibiotics and Antimicrobials

A disturbing phenomenon in contemporary medicine is the prevalence of multidrug-resistant pathogenic bacteria. Efflux pumps contribute strongly to this antimicrobial drug resistance, which leads to the subsequent failure of clinical treatments. The TtgR protein of Pseudomonas putida is a HTH-type tr...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Fernandez-Escamilla, Ana Maria, Fernandez-Ballester, Gregorio, Morel, Bertrand, Casares-Atienza, Salvador, Ramos, Juan Luis
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4589371/
https://ncbi.nlm.nih.gov/pubmed/26422008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138469
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