Phasic Treatment with Interferon Gamma Stimulates Release of Exosomes that Protect Against Spreading Depression

The detrimental effects of T-cell-secreted interferon gamma (IFNγ) on oxidative stress (OS) and demyelination in multiple sclerosis (MS) are well recognized. Recently, we demonstrated that IFNγ-mediated damage to myelin also increases susceptibility to spreading depression (SD; the likely basis of m...

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Bibliografiske detaljer
Udgivet i:J Interferon Cytokine Res
Main Authors: Pusic, Aya D., Kraig, Richard P.
Format: Artigo
Sprog:Inglês
Udgivet: Mary Ann Liebert, Inc. 2015
Fag:
Research Reports
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4589269/
https://ncbi.nlm.nih.gov/pubmed/26083947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jir.2015.0010
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