The expression levels of prolyl oligopeptidase responds not only to neuroinflammation but also to systemic inflammation upon liver failure in rat models and cirrhotic patients

BACKGROUND: Liver failure in experimental animals or in human cirrhosis elicits neuroinflammation. Prolyl oligopeptidase (PREP) has been implicated in neuroinflammatory events in neurodegenerative diseases: PREP protein levels are increased in brain glial cells upon neuroinflammatory insults, but th...

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Veröffentlicht in:J Neuroinflammation
Hauptverfasser: Tenorio-Laranga, Jofre, Montoliu, Carmina, Urios, Amparo, Hernandez-Rabaza, Vicente, Ahabrach, Hanan, García-Horsman, J. Arturo, Felipo, Vicente
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4589196/
https://ncbi.nlm.nih.gov/pubmed/26420028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-015-0404-7
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