Poly(I:C) and CpG-ODN combined aerosolization to treat lung metastases and counter the immunosuppressive microenvironment

The immunostimulatory ability of synthetic oligonucleotides containing CpG motifs (CpG-ODN), agonists of Toll-like receptor 9 (TLR9), can be harnessed to promote antitumor immunity by their application at the tumor site to stimulate local activation of innate immunity; however, particularly in the l...

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Publicat a:Oncoimmunology
Autors principals: Le Noci, Valentino, Tortoreto, Monica, Gulino, Alessandro, Storti, Chiara, Bianchi, Francesca, Zaffaroni, Nadia, Tripodo, Claudio, Tagliabue, Elda, Balsari, Andrea, Sfondrini, Lucia
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2015
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4589046/
https://ncbi.nlm.nih.gov/pubmed/26451303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1040214
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