Pre-differentiation of human neural stem cells into GABAergic neurons prior to transplant results in greater repopulation of the damaged brain and accelerates functional recovery after transient ischemic stroke

INTRODUCTION: Despite attempts to prevent brain injury during the hyperacute phase of stroke, most sufferers end up with significant neuronal loss and functional deficits. The use of cell-based therapies to recover the injured brain offers new hope. In the current study, we employed human neural ste...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Abeysinghe, Hima C. S., Bokhari, Laita, Quigley, Anita, Choolani, Mahesh, Chan, Jerry, Dusting, Gregory J., Crook, Jeremy M., Kobayashi, Nao R., Roulston, Carli L.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4588906/
https://ncbi.nlm.nih.gov/pubmed/26420220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-015-0175-1
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