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Early gestation as the critical time-window for changes in the prenatal environment to affect the adult human blood methylome

Background: The manipulation of pregnancy diets in animals can lead to changes in DNA methylation with phenotypic consequences in the offspring. Human studies have concentrated on the effects of nutrition during early gestation. Lacking in humans is an epigenome-wide association study of DNA methyla...

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Bibliografiska uppgifter
I publikationen:Int J Epidemiol
Huvudupphovsmän: Tobi, Elmar W, Slieker, Roderick C, Stein, Aryeh D, Suchiman, H Eka D, Slagboom, P Eline, van Zwet, Erik W, Heijmans, Bastiaan T, Lumey, LH
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2015
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4588866/
https://ncbi.nlm.nih.gov/pubmed/25944819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ije/dyv043
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