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Inhibition of Small Maf Function in Pancreatic β-Cells Improves Glucose Tolerance Through the Enhancement of Insulin Gene Transcription and Insulin Secretion

The large-Maf transcription factor v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (MafA) has been found to be crucial for insulin transcription and synthesis and for pancreatic β-cell function and maturation. However, insights about the effects of small Maf factors on β-cells are limited....

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Dettagli Bibliografici
Pubblicato in:Endocrinology
Autori principali: Nomoto, Hiroshi, Kondo, Takuma, Miyoshi, Hideaki, Nakamura, Akinobu, Hida, Yoko, Yamashita, Ken-ichiro, Sharma, Arun J., Atsumi, Tatsuya
Natura: Artigo
Lingua:Inglês
Pubblicazione: Endocrine Society 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4588816/
https://ncbi.nlm.nih.gov/pubmed/25763640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2014-1906
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