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Insights Into SMAD4 Loss in Pancreatic Cancer From Inducible Restoration of TGF-β Signaling
Pancreatic ductal adenocarcinoma (PDAC) is the fourth-leading cause of cancer death in the United States. The TGF-β signaling protein SMAD family member 4 is lost in 60% of PDAC, and this has been associated with poorer prognosis. However, the mechanisms by which SMAD4 loss promotes PDAC development...
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| Publicado no: | Mol Endocrinol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Endocrine Society
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4588735/ https://ncbi.nlm.nih.gov/pubmed/26284758 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2015-1102 |
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