Oral Administration of Gintonin Attenuates Cholinergic Impairments by Scopolamine, Amyloid-β Protein, and Mouse Model of Alzheimer’s Disease

Gintonin is a novel ginseng-derived lysophosphatidic acid (LPA) receptor ligand. Oral administration of gintonin ameliorates learning and memory dysfunctions in Alzheimer’s disease (AD) animal models. The brain cholinergic system plays a key role in cognitive functions. The brains of AD patients sho...

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Published in:Mol Cells
Main Authors: Kim, Hyeon-Joong, Shin, Eun-Joo, Lee, Byung-Hwan, Choi, Sun-Hye, Jung, Seok-Won, Cho, Ik-Hyun, Hwang, Sung-Hee, Kim, Joon Yong, Han, Jung-Soo, Chung, ChiHye, Jang, Choon-Gon, Rhim, Hyewon, Kim, Hyoung-Chun, Nah, Seung-Yeol
Format: Artigo
Language:Inglês
Published: Korean Society for Molecular and Cellular Biology 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4588723/
https://ncbi.nlm.nih.gov/pubmed/26255830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14348/molcells.2015.0116
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