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Generation of an alpaca-derived nanobody recognizing γ-H2AX
Post-translational modifications are difficult to visualize in living cells and are conveniently analyzed using antibodies. Single-chain antibody fragments derived from alpacas and called nanobodies can be expressed and bind to the target antigenic sites in living cells. As a proof of concept, we ge...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | FEBS Open Bio |
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| Κύριοι συγγραφείς: | , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Elsevier
2015
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4588710/ https://ncbi.nlm.nih.gov/pubmed/26500838 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fob.2015.09.005 |
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