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Cdh2 stabilizes FGFR1 and contributes to primed-state pluripotency in mouse epiblast stem cells

The cell adhesion molecule Cadherin 2 (Cdh2) plays important roles in somatic cell adhesion, proliferation and migration. Cdh2 is also highly expressed in mouse epiblast stem cells (mEpiSCs), but its function in these cells is unknown. To understand the function of Cdh2 in mEpiSCs, we compared the e...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Takehara, Toshiyuki, Teramura, Takeshi, Onodera, Yuta, Frampton, John, Fukuda, Kanji
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4588589/
https://ncbi.nlm.nih.gov/pubmed/26420260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14722
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