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Doxorubicin-poly (ethylene glycol)-alendronate self-assembled micelles for targeted therapy of bone metastatic cancer

In order to increase the therapeutic effect of doxorubicin (DOX) on bone metastases, a multifunctional micelle was developed by combining pH-sensitive characteristics with bone active targeting capacity. The DOX loaded micelle was self-assembled by using doxorubicin-poly (ethylene glycol)-alendronat...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ye, Wei-liang, Zhao, Yi-pu, Li, Huai-qiu, Na, Ren, Li, Fei, Mei, Qi-bing, Zhao, Ming-gao, Zhou, Si-yuan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4588583/
https://ncbi.nlm.nih.gov/pubmed/26419507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14614
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