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Leptin modulates nutrient reward via inhibitory galanin action on orexin neurons

OBJECTIVE: Leptin modulates food reward via central leptin receptor (LepRb) expressing neurons. Food reward requires stimulation of midbrain dopamine neurons and is modulated by central leptin action, but the exact central mechanisms remain unclear. Stimulatory and inhibitory leptin actions on dopam...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Laque, Amanda, Yu, Sangho, Qualls-Creekmore, Emily, Gettys, Sarah, Schwartzenburg, Candice, Bui, Kelly, Rhodes, Christopher, Berthoud, Hans-Rudolf, Morrison, Christopher D., Richards, Brenda K., Münzberg, Heike
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4588437/
https://ncbi.nlm.nih.gov/pubmed/26500842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2015.07.002
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