E4orf1 induction in adipose tissue promotes insulin-independent signaling in the adipocyte

BACKGROUND/PURPOSE: Type 2 diabetes remains a worldwide epidemic with major pathophysiological changes as a result of chronic insulin resistance. Insulin regulates numerous biochemical pathways related to carbohydrate and lipid metabolism. METHODS: We have generated a novel mouse model that allows u...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Kusminski, Christine M., Gallardo-Montejano, Violeta I., Wang, Zhao V., Hegde, Vijay, Bickel, Perry E., Dhurandhar, Nikhil V., Scherer, Philipp E.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4588421/
https://ncbi.nlm.nih.gov/pubmed/26500839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2015.07.004
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