Ellagic acid, a polyphenolic compound, selectively induces ROS-mediated apoptosis in cancerous B-lymphocytes of CLL patients by directly targeting mitochondria

To investigate the effects ofellagic acid (EA) on the cytotoxicity, B-lymphocytes isolated from CLL patients and healthy individuals. Flow cytometric assay was used to measure the percentage of apoptosis versus necrosis, intracellular active oxygen radicals (ROS), mitochondrial membrane potential (M...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Salimi, Ahmad, Roudkenar, Mehryar Habibi, Sadeghi, Leila, Mohseni, Alireza, Seydi, Enayatollah, Pirahmadi, Nahal, Pourahmad, Jalal
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4588415/
https://ncbi.nlm.nih.gov/pubmed/26418626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2015.08.021
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