Restoration of Na(+)/H(+) exchanger NHE3-containing macrocomplexes ameliorates diabetes-associated fluid loss

Diarrhea is one of the troublesome complications of diabetes, and the underlying causes of this problem are complex. Here, we investigated whether altered electrolyte transport contributes to diabetic diarrhea. We found that the expression of Na(+)/H(+) exchanger NHE3 and several scaffold proteins,...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: He, Peijian, Zhao, Luqing, Zhu, Lixin, Weinman, Edward J., De Giorgio, Roberto, Koval, Michael, Srinivasan, Shanthi, Yun, C. Chris
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4588303/
https://ncbi.nlm.nih.gov/pubmed/26258413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI79552
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