The cortical thickness phenotype of individuals with DISC1 translocation resembles schizophrenia

BACKGROUND. The disrupted in schizophrenia 1 (DISC1) gene locus was originally identified in a Scottish pedigree with a high incidence of psychiatric disorders that is associated with a balanced t(1;11)(q42.1;q14.3) chromosomal translocation. Here, we investigated whether members of this family carr...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Doyle, Orla M., Bois, Catherine, Thomson, Pippa, Romaniuk, Liana, Whitcher, Brandon, Williams, Steven C.R., Turkheimer, Federico E., Stefansson, Hreinn, McIntosh, Andrew M., Mehta, Mitul A., Lawrie, Stephen M.
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2015
Subjects:
Clinical Medicine
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4588302/
https://ncbi.nlm.nih.gov/pubmed/26301809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI82636
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