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Anti–PD-1/PD-L1 therapy of human cancer: past, present, and future

Major progress has been made toward our understanding of the programmed death-1/programmed death ligand-1 (PD-1/PD-L1) pathway (referred to as the PD pathway). mAbs are already being used to block the PD pathway to treat human cancers (anti-PD therapy), especially advanced solid tumors. This therapy...

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Bibliografske podrobnosti
izdano v:J Clin Invest
Main Authors: Chen, Lieping, Han, Xue
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4588282/
https://ncbi.nlm.nih.gov/pubmed/26325035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI80011
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