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Heavy water and (15)N labeling with NanoSIMS analysis reveals growth-rate dependent metabolic heterogeneity in chemostats

To measure single cell microbial activity and substrate utilization patterns in environmental systems, we employ a new technique using stable isotope labeling of microbial populations with heavy water (a passive tracer) and (15)N ammonium in combination with multi-isotope imaging mass spectrometry....

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Bibliografske podrobnosti
izdano v:Environ Microbiol
Main Authors: Kopf, Sebastian H., McGlynn, Shawn E., Green-Saxena, Abigail, Guan, Yunbin, Newman, Dianne K., Orphan, Victoria J.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4587896/
https://ncbi.nlm.nih.gov/pubmed/25655651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/1462-2920.12752
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